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Effect of Hormone Modulations on Donor-Derived Spermatogenesis or Colonization after Syngeneic and Xenotransplantation in Mice

BACKGROUND: Cytotoxic cancer treatments, such as irradiation, can cause permanent sterility in male mammals due to the loss of spermatogonial stem cells (SSCs). In animal models, spermatogenesis could be restored from transplanted SSCs. Previously we showed that transient suppression of FSH, LH, and...

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Detalhes bibliográficos
Publicado no:Andrology
Main Authors: SHETTY, GUNAPALA, WU, ZHUANG, ANH LAM, TRUONG NGUYEN, PHAN, THIEN TRONG, ORWIG, KYLE E, MEISTRICH, MARVIN L
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422689/
https://ncbi.nlm.nih.gov/pubmed/30471208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/andr.12571
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