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Cefuroxime plasma and tissue concentrations in patients undergoing elective cardiac surgery: Continuous vs bolus application. A pilot study

AIMS: Surgical site infections contribute to morbidity and mortality after surgery. The authors hypothesized that higher antibiotic tissue concentrations can be reached for a prolonged time span by continuous administration of prophylactic cefuroxime compared to bolus administration. METHODS: Twelve...

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Veröffentlicht in:Br J Clin Pharmacol
Hauptverfasser: Skhirtladze‐Dworschak, Keso, Hutschala, Doris, Reining, Georg, Dittrich, Peter, Bartunek, Anna, Dworschak, Martin, Tschernko, Edda M.
Format: Artigo
Sprache:Inglês
Veröffentlicht: John Wiley and Sons Inc. 2019
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Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422641/
https://ncbi.nlm.nih.gov/pubmed/30636060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13865
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