Cefuroxime plasma and tissue concentrations in patients undergoing elective cardiac surgery: Continuous vs bolus application. A pilot study

AIMS: Surgical site infections contribute to morbidity and mortality after surgery. The authors hypothesized that higher antibiotic tissue concentrations can be reached for a prolonged time span by continuous administration of prophylactic cefuroxime compared to bolus administration. METHODS: Twelve...

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Vydáno v:Br J Clin Pharmacol
Hlavní autoři: Skhirtladze‐Dworschak, Keso, Hutschala, Doris, Reining, Georg, Dittrich, Peter, Bartunek, Anna, Dworschak, Martin, Tschernko, Edda M.
Médium: Artigo
Jazyk:Inglês
Vydáno: John Wiley and Sons Inc. 2019
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Original Articles
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422641/
https://ncbi.nlm.nih.gov/pubmed/30636060
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13865
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