Antibiotics are associated with decreased progression-free survival of advanced melanoma patients treated with immune checkpoint inhibitors

Background: The gut microbiota has been shown to be an important determinant of the efficacy of immune checkpoint inhibitions (ICI) in cancer. Several lines of evidence suggest that antibiotic (ATB) usage prior to or within the first month of ICI initiation negatively impacts clinical outcomes. Meth...

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Veröffentlicht in:Oncoimmunology
Hauptverfasser: Elkrief, Arielle, El Raichani, Layal, Richard, Corentin, Messaoudene, Meriem, Belkaid, Wiam, Malo, Julie, Belanger, Karl, Miller, Wilson, Jamal, Rahima, Letarte, Nathalie, Wong, Philip, Routy, Bertrand
Format: Artigo
Sprache:Inglês
Veröffentlicht: Taylor & Francis 2019
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Original Research
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422373/
https://ncbi.nlm.nih.gov/pubmed/30906663
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/2162402X.2019.1568812
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