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Novel scaffolds for modulation of TRPV1 identified with pharmacophore modeling and virtual screening
AIM: The transient receptor potential vanilloid type 1 (TRPV1) is responsible for pain perception in the peripheral nervous system (PNS). TRPV1 is thus considered a versatile target for development of non-opioid analgesics. RESULTS: Pharmacophore-based clustering of a publicly available data set of...
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| Published in: | Future Med Chem |
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| Main Authors: | , , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6422283/ https://ncbi.nlm.nih.gov/pubmed/25826358 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4155/fmc.14.168 |
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