Transforming growth factor β (TGFβ) induces NUAK kinase expression to fine-tune its signaling output

TGFβ signaling via SMAD proteins and protein kinase pathways up- or down-regulates the expression of many genes and thus affects physiological processes, such as differentiation, migration, cell cycle arrest, and apoptosis, during developmental or adult tissue homeostasis. We here report that NUAK f...

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Veröffentlicht in:J Biol Chem
Hauptverfasser: Kolliopoulos, Constantinos, Raja, Erna, Razmara, Masoud, Heldin, Paraskevi, Heldin, Carl-Henrik, Moustakas, Aristidis, van der Heide, Lars P.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2019
Schlagworte:
Signal Transduction
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422081/
https://ncbi.nlm.nih.gov/pubmed/30622137
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.004984
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