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Plasmodium chabaudi AS Infection Induces CD4(+) Th1 Cells and Foxp3(+)T-bet(+) Regulatory T Cells That Express CXCR3 and Migrate to CXCR3 Ligands

Control and elimination of blood-stage Plasmodium chabaudi AS infection requires CD4(+) Th1 cells that secrete IFN-γ and T follicular help (Tfh) cells together with B cell production of antibody. Foxp3(+) regulatory T cells (Tregs) are also crucial to protect the host from immunopathology and severe...

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Udgivet i:Front Immunol
Main Authors: Berretta, Floriana, Piccirillo, Ciriaco A., Stevenson, Mary M.
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6422055/
https://ncbi.nlm.nih.gov/pubmed/30915078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00425
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