Hemochromatosis (HFE) Gene Variants Are Associated with Increased Mitochondrial DNA Levels During HIV-1 Infection and Antiretroviral Therapy

Some HIV-associated complications involve mitochondrial dysfunction and may be less common in individuals with iron-loading HFE (hemochromatosis gene) variants. We evaluated HFE 845A and 187G alleles in relation to mitochondrial DNA (mtDNA) levels in peripheral blood mononuclear cells from 85 indivi...

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Detalhes bibliográficos
Publicado no:AIDS Res Hum Retroviruses
Main Authors: Kallianpur, Asha R., Gerschenson, Mariana, Hulgan, Todd, Kaur, Harpreet, Clifford, David B., Haas, David W., Murdock, Deborah G., McArthur, Justin C., Samuels, David C., Simpson, David M.
Formato: Artigo
Idioma:Inglês
Publicado em: Mary Ann Liebert, Inc., publishers 2018
Assuntos:
Pathogenesis
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421985/
https://ncbi.nlm.nih.gov/pubmed/29968489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/aid.2018.0025
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