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Can broadly neutralizing monoclonal antibodies lead us to a hepatitis C virus vaccine?

While licensed vaccines elicit protective antibody responses against a variety of viral infections, an effective vaccine for hepatitis C virus (HCV) has remained elusive. The extraordinary genetic diversity of HCV and the ability of the virus to evade the immune response have hindered vaccine develo...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Trends Microbiol
Hauptverfasser: Kinchen, Valerie J., Cox, Andrea L., Bailey, Justin R.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421862/
https://ncbi.nlm.nih.gov/pubmed/29703495
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tim.2018.04.002
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