HHLA2 in intrahepatic cholangiocarcinoma: an immune checkpoint with prognostic significance and wider expression compared with PD-L1

BACKGROUND: Intrahepatic cholangiocarcinoma (ICC) is a highly mortal malignancy with limited therapeutic options. Immunotherapies targeting PD-1/PD-L1 pathway represent a promising treatment for ICC. However, PD-L1 expression and microsatellite instability are not common in ICC. This study aimed to...

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Detalhes bibliográficos
Publicado no:J Immunother Cancer
Main Authors: Jing, Chu-Yu, Fu, Yi-Peng, Yi, Yong, Zhang, Mei-Xia, Zheng, Su-Su, Huang, Jin-Long, Gan, Wei, Xu, Xin, Lin, Jia-Jia, Zhang, Juan, Qiu, Shuang-Jian, Zhang, Bo-Heng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421676/
https://ncbi.nlm.nih.gov/pubmed/30885276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40425-019-0554-8
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