Activation of AMPK in Human Placental Explants Impairs Mitochondrial Function and Cellular Metabolism

OBJECTIVE: Adenosine monophosphate–activated protein kinase (AMPK) is a cellular energy sensor whose phosphorylation increases energy production. We sought to evaluate the placenta-specific effect of AMPK activation on the handling of nutrients required for fetal development. METHODS: Explants were...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Reprod Sci
Main Authors: Landau, Daphne, Haghiac, Maricela, Minium, Judi, Skomorovska-Prokvolit, Yelenna, Calabuig-Navarro, Virtu, O’Tierney-Ginn, Perrie
Format: Artigo
Jezik:Inglês
Izdano: SAGE Publications 2018
Teme:
Original Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421623/
https://ncbi.nlm.nih.gov/pubmed/29788824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1933719118776803
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