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Harnessing Polypharmacology with Medicinal Chemistry

[Image: see text] Polypharmacology has expanded enormously over the last ten years, with several multitarget drugs (MTDs) already in the market. This Viewpoint provides a basis for a discussion about the critical need to develop MTDs in a more rationale and conscious way. A checklist to maximize suc...

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Veröffentlicht in:ACS Med Chem Lett
1. Verfasser: Bolognesi, Maria Laura
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2019
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421528/
https://ncbi.nlm.nih.gov/pubmed/30891125
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.9b00039
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