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Major histocompatibility complex class I diversity limits the repertoire of T cell receptors
Major histocompatibility complex (MHC) genes encode proteins that initiate adaptive immune responses through the presentation of foreign antigens to T cells. The high polymorphism found at these genes, thought to be promoted and maintained by pathogen-mediated selection, contrasts with the limited n...
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| Publié dans: | Proc Natl Acad Sci U S A |
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| Auteurs principaux: | , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
National Academy of Sciences
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6421458/ https://ncbi.nlm.nih.gov/pubmed/30796191 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1807864116 |
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