Par3 is essential for the establishment of planar cell polarity of inner ear hair cells

In the inner ear sensory epithelia, stereociliary hair bundles atop sensory hair cells are mechanosensory apparatus with planar polarized structure and orientation. This is established during development by the concerted action of tissue-level, intercellular planar cell polarity (PCP) signaling and...

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Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Landin Malt, Andre, Dailey, Zachary, Holbrook-Rasmussen, Julia, Zheng, Yuqiong, Hogan, Arielle, Du, Quansheng, Lu, Xiaowei
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 2019
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PNAS Plus
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421412/
https://ncbi.nlm.nih.gov/pubmed/30814219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816333116
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