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Par3 is essential for the establishment of planar cell polarity of inner ear hair cells

In the inner ear sensory epithelia, stereociliary hair bundles atop sensory hair cells are mechanosensory apparatus with planar polarized structure and orientation. This is established during development by the concerted action of tissue-level, intercellular planar cell polarity (PCP) signaling and...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Landin Malt, Andre, Dailey, Zachary, Holbrook-Rasmussen, Julia, Zheng, Yuqiong, Hogan, Arielle, Du, Quansheng, Lu, Xiaowei
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421412/
https://ncbi.nlm.nih.gov/pubmed/30814219
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1816333116
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