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Transcriptional Analysis of the Human IgE-Expressing Plasma Cell Differentiation Pathway

IgE is secreted by plasma cells (PCs) and is central to allergic disease. Using an ex vivo tonsil B cell culture system, which mimics the Th2 responses in vivo, we have recently characterized the development pathway of human IgE-expressing PCs. In this system, as in mice, we reported the predisposit...

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Detalhes bibliográficos
Publicado no:Front Immunol
Main Authors: Ramadani, Faruk, Bowen, Holly, Gould, Hannah J., Fear, David J.
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421273/
https://ncbi.nlm.nih.gov/pubmed/30915071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00402
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