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Novel insights into molecular chaperone regulation of ribonucleotide reductase

The molecular chaperones Hsp70 and Hsp90 bind and fold a significant proportion of the proteome. They are responsible for the activity and stability of many disease related proteins including those in cancer. Substantial effort has been devoted to developing a range of chaperone inhibitors for clini...

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Detalhes bibliográficos
Publicado no:Curr Genet
Main Authors: Knighton, Laura E., Delgado, Lena E., Truman, Andrew W.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6421096/
https://ncbi.nlm.nih.gov/pubmed/30519713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00294-018-0916-7
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