Polyclonal HIV envelope-specific breast milk antibodies limit founder SHIV acquisition and cell-associated virus loads in infant rhesus monkeys.

Breast milk HIV-1 transmission is currently the predominant contributor to pediatric HIV infections. Yet, only ~10% of breastfeeding infants born to untreated HIV-infected mothers become infected. This study assessed the protective capacity of natural HIV envelope-specific antibodies isolated from m...

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Publicat a:Mucosal Immunol
Autors principals: Himes, Jonathon E., Goswami, Ria, Mangan, Riley J., Kumar, Amit, Jeffries, Thomas L., Eudailey, Joshua A., Heimsath, Holly, Nguyen, Quang N., Pollara, Justin, LaBranche, Celia, Chen, Meng, Vandergrift, Nathan A., Peacock, James W., Schiro, Faith, Midkiff, Cecily, Ferrari, Guido, Montefiori, David C., Alvarez-Hernandez, Xavier, Pyone Aye, Pyone, Permar, Sallie R.
Format: Artigo
Idioma:Inglês
Publicat: 2018
Matèries:
Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420805/
https://ncbi.nlm.nih.gov/pubmed/30115994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41385-018-0067-7
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