The MurG glycosyltransferase provides an oligomeric scaffold for the cytoplasmic steps of peptidoglycan biosynthesis in the human pathogen Bordetella pertussis

Peptidoglycan is a major component of the bacterial cell wall and thus a major determinant of cell shape. Its biosynthesis is initiated by several sequential reactions catalyzed by cytoplasmic Mur enzymes. Mur ligases (MurC, -D, -E, and -F) are essential for bacteria, metabolize molecules not presen...

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Veröffentlicht in:Sci Rep
Hauptverfasser: Laddomada, Federica, Miyachiro, Mayara M., Jessop, Matthew, Patin, Delphine, Job, Viviana, Mengin-Lecreulx, Dominique, Le Roy, Aline, Ebel, Christine, Breyton, Cécile, Gutsche, Irina, Dessen, Andréa
Format: Artigo
Sprache:Inglês
Veröffentlicht: Nature Publishing Group UK 2019
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420597/
https://ncbi.nlm.nih.gov/pubmed/30874582
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40966-z
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