Electroporation-Mediated Immunization of a Candidate DNA Vaccine Expressing Dengue Virus Serotype 4 prM-E Antigen Confers Long-Term Protection in Mice

Dengue fever, caused by dengue viruses (DENVs), is a widespread mosquito-borne zoonotic disease; however, there is no available anti-dengue vaccine for worldwide use. In the current study, a DNA vaccine candidate (pV-D4ME) expressing prM-E protein of DENV serotype 4 (DENV-4) was constructed, and its...

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Publicado en:Virol Sin
Autores principales: Sheng, Ziyang, Chen, Hui, Feng, Kaihao, Gao, Na, Wang, Ran, Wang, Peigang, Fan, Dongying, An, Jing
Formato: Artigo
Lenguaje:Inglês
Publicado: Springer Singapore 2019
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420567/
https://ncbi.nlm.nih.gov/pubmed/30790202
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12250-019-00090-8
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