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Chronic insulinopenia/hyperglycemia decrease cannabinoid CB(1) receptor density and impair glucose uptake in the mouse forebrain
Both endocannabinoids and insulin regulate peripheral and cerebral glucose homeostasis via convergent signaling pathways that are impacted by diabetes. Here we asked how glucose metabolism and important facets of insulin signaling are affected in the forebrain of cannabinoid CB(1) receptor knockout...
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| Udgivet i: | Brain Res Bull |
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| Main Authors: | , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6420377/ https://ncbi.nlm.nih.gov/pubmed/30721768 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainresbull.2019.01.024 |
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