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Nuclear genetic regulation of the human mitochondrial transcriptome

Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable variatio...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Ali, Aminah T, Boehme, Lena, Carbajosa, Guillermo, Seitan, Vlad C, Small, Kerrin S, Hodgkinson, Alan
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420317/
https://ncbi.nlm.nih.gov/pubmed/30775970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41927
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