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Nuclear genetic regulation of the human mitochondrial transcriptome

Mitochondria play important roles in cellular processes and disease, yet little is known about how the transcriptional regime of the mitochondrial genome varies across individuals and tissues. By analyzing >11,000 RNA-sequencing libraries across 36 tissue/cell types, we find considerable variatio...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:eLife
Prif Awduron: Ali, Aminah T, Boehme, Lena, Carbajosa, Guillermo, Seitan, Vlad C, Small, Kerrin S, Hodgkinson, Alan
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: eLife Sciences Publications, Ltd 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420317/
https://ncbi.nlm.nih.gov/pubmed/30775970
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.41927
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