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Rapid pathology of lumpectomy margins with open-top light-sheet (OTLS) microscopy

Open-top light-sheet microscopy is a technique that can potentially enable rapid ex vivo inspection of large tissue surfaces and volumes. Here, we have optimized an open-top light-sheet (OTLS) microscope and image-processing workflow for the comprehensive examination of surgical margin surfaces, and...

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Bibliographic Details
Published in:Biomed Opt Express
Main Authors: Chen, Ye, Xie, Weisi, Glaser, Adam K., Reder, Nicholas P., Mao, Chenyi, Dintzis, Suzanne M., Vaughan, Joshua C., Liu, Jonathan T. C.
Format: Artigo
Language:Inglês
Published: Optical Society of America 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420271/
https://ncbi.nlm.nih.gov/pubmed/30891344
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1364/BOE.10.001257
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