Cryptococcosis-associated Immune Reconstitution Inflammatory Syndrome is associated with Dysregulation of IL-7/IL-7 Receptor Signaling Pathway in T-cells and Monocyte Activation

BACKGROUND: Systemic levels of interleukin (IL)-7 at antiretroviral therapy (ART) initiation have previously been shown to be predictive of HIV-linked paradoxical cryptococcosis-associated immune reconstitution inflammatory syndrome (C-IRIS). We therefore explored IL-7/IL-7 receptor (IL-7/IL-7R) sig...

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Vydáno v:J Acquir Immune Defic Syndr
Hlavní autoři: Akilimali, Ngomu Akeem, Muema, Daniel M., Specht, Charles, Chang, Christina C., Moosa, Mahomed-Yunus S., Levitz, Stuart M., Lewin, Sharon R., French, Martyn A., Ndung’u, Thumbi
Médium: Artigo
Jazyk:Inglês
Vydáno: 2019
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6420066/
https://ncbi.nlm.nih.gov/pubmed/30649031
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000001946
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