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Agents to treat BRAF-mutant lung cancer

BRAF mutations are seen in up to 3.5–4% of the non-small cell lung cancer (NSCLC) patients. BRAF V600E mutations account for 50% of these cases, and the remaining BRAF mutations are non-V600E. The biologic behavior of BRAF-mutated lung tumors tends to be more aggressive and resistant to chemotherapy...

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Dettagli Bibliografici
Pubblicato in:Drugs Context
Autori principali: Alvarez, Jean G Bustamante, Otterson, Gregory A
Natura: Artigo
Lingua:Inglês
Pubblicazione: BioExcel Publishing Ltd 2019
Soggetti:
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419923/
https://ncbi.nlm.nih.gov/pubmed/30899313
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7573/dic.212566
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