The miR 495-UBE2C-ABCG2/ERCC1 axis reverses cisplatin resistance by downregulating drug resistance genes in cisplatin-resistant non-small cell lung cancer cells

Cisplatin (DDP) resistance has become the leading cause of mortality in non-small cell lung cancer (NSCLC). miRNA dysregulation significantly contributes to tumor progression. In this study, we found that miR-495 was significantly downregulated in lung cancer tissue specimens. This study aimed to el...

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Detalhes bibliográficos
Publicado no:EBioMedicine
Main Authors: Guo, Jiwei, Jin, Dan, Wu, Yan, Yang, Lijuan, Du, Jing, Gong, Kaikai, Chen, Weiwei, Dai, Juanjuan, Miao, Shuang, Xi, Sichuan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Research paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419862/
https://ncbi.nlm.nih.gov/pubmed/30146342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ebiom.2018.08.001
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