In vitro activity of apramycin against multidrug-, carbapenem- and aminoglycoside-resistant Enterobacteriaceae and Acinetobacter baumannii

OBJECTIVES: Widespread antimicrobial resistance often limits the availability of therapeutic options to only a few last-resort drugs that are themselves challenged by emerging resistance and adverse side effects. Apramycin, an aminoglycoside antibiotic, has a unique chemical structure that evades al...

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Detalhes bibliográficos
Publicado no:J Antimicrob Chemother
Main Authors: Juhas, Mario, Widlake, Emma, Teo, Jeanette, Huseby, Douglas L, Tyrrell, Jonathan M, Polikanov, Yury S, Ercan, Onur, Petersson, Anna, Cao, Sha, Aboklaish, Ali F, Rominski, Anna, Crich, David, Böttger, Erik C, Walsh, Timothy R, Hughes, Diarmaid, Hobbie, Sven N
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Original Research
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419615/
https://ncbi.nlm.nih.gov/pubmed/30629184
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/jac/dky546
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