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CoCl(2) simulated hypoxia induce cell proliferation and alter the expression pattern of hypoxia associated genes involved in angiogenesis and apoptosis

BACKGROUND/AIMS: Hypoxia microenvironment plays a crucial role during tumor progression and it tends to exhibit poor prognosis and make resistant to various conventional therapies. HIF-1α acts as an important transcriptional regulator directly or indirectly associated with genes involved in cell pro...

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Bibliografski detalji
Izdano u:Biol Res
Glavni autori: Rana, Nishant Kumar, Singh, Priya, Koch, Biplob
Format: Artigo
Jezik:Inglês
Izdano: BioMed Central 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419504/
https://ncbi.nlm.nih.gov/pubmed/30876462
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40659-019-0221-z
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