Persistence of chloroquine resistance alleles in malaria endemic countries: a systematic review of burden and risk factors

BACKGROUND: Chloroquine, a previous highly efficacious, easy to use and affordable anti-malarial agent was withdrawn from malaria endemic regions due to high levels of resistance. This review collated evidence from published-reviewed articles to establish prevalence of Pfcrt 76T and Pfmdr-1 86Y alle...

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Vydáno v:Malar J
Hlavní autoři: Ocan, Moses, Akena, Dickens, Nsobya, Sam, Kamya, Moses R., Senono, Richard, Kinengyere, Alison Annet, Obuku, Ekwaro A.
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
Research
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419488/
https://ncbi.nlm.nih.gov/pubmed/30871535
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12936-019-2716-z
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