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Rational protein design of Bacillus sp. MN chitosanase for altered substrate binding and production of specific chitosan oligomers

BACKGROUND: Partially acetylated chito-oligosaccharides (paCOS) have a variety of potential applications in different fields, but to harness their benefits, pure paCOS or well-defined paCOS mixtures are essential. For example, if one could produce fully acetylated (A(4)) and fully deacetylated (D(4)...

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Detalhes bibliográficos
Publicado no:J Biol Eng
Main Authors: Gercke, David, Regel, Eva K., Singh, Ratna, Moerschbacher, Bruno M.
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419424/
https://ncbi.nlm.nih.gov/pubmed/30918529
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13036-019-0152-9
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