A multicenter open-label phase II trial to evaluate nivolumab and ipilimumab for 2nd line therapy in elderly patients with advanced esophageal squamous cell cancer (RAMONA)

BACKGROUND: Advanced esophageal squamous cell cancer (ESCC) is frequently diagnosed in elderly patients. The impact of 2nd line chemotherapy is poorly defined. Recent data demonstrated effectiveness of checkpoint inhibitors in different squamous cell carcinomas. Therefore, we assess combined nivolum...

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Detalhes bibliográficos
Publicado no:BMC Cancer
Main Authors: Meindl-Beinker, Nadja M., Betge, Johannes, Gutting, Tobias, Burgermeister, Elke, Belle, Sebastian, Zhan, Tianzuo, Schulte, Nadine, Maenz, Martin, Ebert, Matthias P., Haertel, Nicolai
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Study Protocol
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6419339/
https://ncbi.nlm.nih.gov/pubmed/30871493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5446-2
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