Enhancing the antitumor functions of invariant natural killer T cells using a soluble CD1d-CD19 fusion protein

Invariant natural killer T (iNKT) cells comprise a unique lineage of CD1d-restricted lipid-reactive T lymphocytes that potently kill tumor cells and exhibit robust immunostimulatory functions. Optimal tumor-directed iNKT cell responses often require expression of the antigen-presenting molecule CD1d...

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Detalhes bibliográficos
Publicado no:Blood Adv
Main Authors: Das, Rupali, Guan, Peng, Wiener, Susan J., Patel, Nishant P., Gohl, Trevor G., Evans, Elizabeth, Zauderer, Maurice, Nichols, Kim E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Hematology 2019
Assuntos:
Immunobiology and Immunotherapy
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418505/
https://ncbi.nlm.nih.gov/pubmed/30858151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018028886
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