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Interleukin-2–inducible T-cell kinase inhibitors modify functional polarization of human peripheral T-cell lymphoma cells

ITK inhibitors perturb functional changes due to polarizing culture conditions in normal human tonsil CD4(+) T cells. Primary human PTCL cells alter their functional properties in culture and ITK inhibitors modify these changes.

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Détails bibliographiques
Publié dans:Blood Adv
Auteurs principaux: Mamand, Sami, Carr, Matthew, Allchin, Rebecca L., Ahearne, Matthew J., Wagner, Simon D.
Format: Artigo
Langue:Inglês
Publié: American Society of Hematology 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418494/
https://ncbi.nlm.nih.gov/pubmed/30814054
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/bloodadvances.2018027821
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