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Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy

Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have been shown to reprogram injured cells by activating regenerative processes. We herein investigate the potential therapeutic effect of EVs, shed by human bone marrow MSCs and by human liver stem-like cells (HLSCs...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Grange, Cristina, Tritta, Stefania, Tapparo, Marta, Cedrino, Massimo, Tetta, Ciro, Camussi, Giovanni, Brizzi, Maria Felice
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418239/
https://ncbi.nlm.nih.gov/pubmed/30872726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41100-9
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