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Stem cell-derived extracellular vesicles inhibit and revert fibrosis progression in a mouse model of diabetic nephropathy

Extracellular vesicles (EVs) that are derived from mesenchymal stromal cells (MSCs) have been shown to reprogram injured cells by activating regenerative processes. We herein investigate the potential therapeutic effect of EVs, shed by human bone marrow MSCs and by human liver stem-like cells (HLSCs...

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Publicat a:Sci Rep
Autors principals: Grange, Cristina, Tritta, Stefania, Tapparo, Marta, Cedrino, Massimo, Tetta, Ciro, Camussi, Giovanni, Brizzi, Maria Felice
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2019
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418239/
https://ncbi.nlm.nih.gov/pubmed/30872726
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41100-9
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