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Steroidogenic Factor 1 (Nr5a1) is Required for Sertoli Cell Survival Post Sex Determination
The elevated level of Steroidogenic Factor 1 (Nr5a1, Sf-1) expression in the male gonadal development pathway, post sex determination, implies a vital role in testis gonadal differentiation. In this study we generated Sertoli cell-specific Nr5a1 KO mice (SC-SF-1(−/−)) at E14.5, which coincides with...
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| Udgivet i: | Sci Rep |
|---|---|
| Main Authors: | , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group UK
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6418149/ https://ncbi.nlm.nih.gov/pubmed/30872705 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41051-1 |
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