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Timing constraints of action potential evoked Ca(2+) current and transmitter release at a central nerve terminal

The waveform of presynaptic action potentials (APs) regulates the magnitude of Ca(2+) currents (I(Ca)) and neurotransmitter release. However, how APs control the timing of synaptic transmission remains unclear. Using the calyx of Held synapse, we find that Na(+) and K(+) channels affect the timing b...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Chao, Owen Y., Yang, Yi-Mei
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418091/
https://ncbi.nlm.nih.gov/pubmed/30872753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-41120-5
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