Modeling CADASIL vascular pathologies with patient-derived induced pluripotent stem cells

Cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL) is a rare hereditary cerebrovascular disease caused by a NOTCH3 mutation. However, the underlying cellular and molecular mechanisms remain unidentified. Here, we generated non-integrative induced plu...

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Détails bibliographiques
Publié dans:Protein Cell
Auteurs principaux: Ling, Chen, Liu, Zunpeng, Song, Moshi, Zhang, Weiqi, Wang, Si, Liu, Xiaoqian, Ma, Shuai, Sun, Shuhui, Fu, Lina, Chu, Qun, Belmonte, Juan Carlos Izpisua, Wang, Zhaoxia, Qu, Jing, Yuan, Yun, Liu, Guang-Hui
Format: Artigo
Langue:Inglês
Publié: Higher Education Press 2019
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6418078/
https://ncbi.nlm.nih.gov/pubmed/30778920
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13238-019-0608-1
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