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“Physiological Dysregulation” as a Promising Measure of Robustness and Resilience in Studies of Aging and a New Indicator of Preclinical Disease

Recently suggested novel implementation of the statistical distance measure (D(M)) for evaluating “physiological dysregulation” (PD) in aging individuals (based on measuring deviations of multiple biomarkers from baseline or normal physiological states) allows reducing high-dimensional biomarker spa...

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Detalhes bibliográficos
Publicado no:J Gerontol A Biol Sci Med Sci
Main Authors: Arbeev, Konstantin G, Ukraintseva, Svetlana V, Bagley, Olivia, Zhbannikov, Ilya Y, Cohen, Alan A, Kulminski, Alexander M, Yashin, Anatoliy I
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6417443/
https://ncbi.nlm.nih.gov/pubmed/29939206
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/gerona/gly136
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