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The microRNAs let-7 and miR-9 down-regulate the axon-guidance genes Ntn1 and Dcc during peripheral nerve regeneration

Axon guidance helps growing neural axons to follow precise paths to reach their target locations. It is a critical step for both the formation and regeneration of neuronal circuitry. Netrin-1 (Ntn1) and its receptor, deleted in colorectal carcinoma (Dcc) are essential factors for axon guidance, but...

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Pubblicato in:J Biol Chem
Autori principali: Wang, Xinghui, Chen, Qianqian, Yi, Sheng, Liu, Qianyan, Zhang, Ruirui, Wang, Pan, Qian, Tianmei, Li, Shiying
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Biochemistry and Molecular Biology 2019
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416429/
https://ncbi.nlm.nih.gov/pubmed/30626732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA119.007389
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