Tryptophan metabolism and its relationship with central nervous system toxicity in people living with HIV switching from efavirenz to dolutegravir

The mechanisms underlying central nervous system (CNS) toxicities in antiretroviral-treated persons living with HIV (PLWH) remain elusive. We investigated the associations between markers of tryptophan metabolism and measurements of CNS toxicity in PLWH. In a prospective study, virologically suppres...

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Publicat a:J Neurovirol
Autors principals: Keegan, Michael R., Winston, Alan, Higgs, Chris, Fuchs, Dietmar, Boasso, Adriano, Nelson, Mark
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416362/
https://ncbi.nlm.nih.gov/pubmed/30478800
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s13365-018-0688-3
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