Duodenal bacterial proteolytic activity determines sensitivity to dietary antigen through protease-activated receptor-2

Microbe-host interactions are generally homeostatic, but when dysfunctional, they can incite food sensitivities and chronic diseases. Celiac disease (CeD) is a food sensitivity characterized by a breakdown of oral tolerance to gluten proteins in genetically predisposed individuals, although the unde...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Caminero, Alberto, McCarville, Justin L., Galipeau, Heather J., Deraison, Celine, Bernier, Steve P., Constante, Marco, Rolland, Corinne, Meisel, Marlies, Murray, Joseph A., Yu, Xuechen B., Alaedini, Armin, Coombes, Brian K., Bercik, Premysl, Southward, Carolyn M., Ruf, Wolfram, Jabri, Bana, Chirdo, Fernando G., Casqueiro, Javier, Surette, Michael G., Vergnolle, Nathalie, Verdu, Elena F.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416356/
https://ncbi.nlm.nih.gov/pubmed/30867416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-019-09037-9
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