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Tonic inhibition of murine proximal colon is due to nitrergic suppression of Ca(2+) signaling in interstitial cells of Cajal

Spontaneous excitability and contractions of colonic smooth muscle cells (SMCs) are normally suppressed by inputs from inhibitory motor neurons, a behavior known as tonic inhibition. The post-junctional cell(s) mediating tonic inhibition have not been elucidated. We investigated the post-junctional...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Drumm, Bernard T., Rembetski, Benjamin E., Baker, Salah A., Sanders, Kenton M.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416298/
https://ncbi.nlm.nih.gov/pubmed/30867452
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-39729-7
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