The influence of the host microbiome on 3,4-methylenedioxymethamphetamine (MDMA)-induced hyperthermia and vice versa

Hyperthermia induced by 3,4-methylenedioxymethamphetamine (MDMA) can be life-threatening. Here, we investigate the role of the gut microbiome and TGR5 bile acid receptors in MDMA-mediated hyperthermia. Fourteen days prior to treatment with MDMA, male Sprague-Dawley rats were provided water or water...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Ridge, Emily A., Pachhain, Sudhan, Choudhury, Sayantan Roy, Bodnar, Sara R., Larsen, Ray A., Phuntumart, Vipaporn, Sprague, Jon E.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416279/
https://ncbi.nlm.nih.gov/pubmed/30867489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-40803-3
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