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Tasmanian devils with contagious cancer exhibit a constricted T-cell repertoire diversity

The Tasmanian devil (Sarcophilus harrisii) is threatened by a contagious cancer, known as Devil Facial Tumour Disease (DFTD). A highly diverse T-cell receptor (TCR) repertoire is crucial for successful host defence against cancers. By investigating TCR beta chain diversity in devils of different age...

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Bibliografske podrobnosti
izdano v:Commun Biol
Main Authors: Cheng, Yuanyuan, Makara, Mariano, Peel, Emma, Fox, Samantha, Papenfuss, Anthony T., Belov, Katherine
Format: Artigo
Jezik:Inglês
Izdano: Nature Publishing Group UK 2019
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6416256/
https://ncbi.nlm.nih.gov/pubmed/30886908
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0342-5
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