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Cellular microRNA detection with miRacles: microRNA- activated conditional looping of engineered switches

MicroRNAs are short noncoding regulatory RNAs that are increasingly used as disease biomarkers. Detection of microRNAs can be arduous and expensive and often requires amplification, labeling, or radioactive probes. Here, we report a single-step, nonenzymatic microRNA detection assay using conformati...

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Detalhes bibliográficos
Publicado no:Sci Adv
Main Authors: Chandrasekaran, Arun Richard, MacIsaac, Molly, Dey, Paromita, Levchenko, Oksana, Zhou, Lifeng, Andres, Madeline, Dey, Bijan K., Halvorsen, Ken
Formato: Artigo
Idioma:Inglês
Publicado em: American Association for the Advancement of Science 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415953/
https://ncbi.nlm.nih.gov/pubmed/30891499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/sciadv.aau9443
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