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STIM- and Orai-mediated Calcium Entry Controls NF-κB Activity and Function in Lymphocytes

The central role of Ca(2+) signaling in the development of functional immunity and tolerance is well established. These signals are initiated by antigen binding to cognate receptors on lymphocytes that trigger store operated Ca(2+) entry (SOCE). The underlying mechanism of SOCE in lymphocytes involv...

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Detalhes bibliográficos
Publicado no:Cell Calcium
Main Authors: Berry, Corbett T., May, Michael J., Freedman, Bruce D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415950/
https://ncbi.nlm.nih.gov/pubmed/30048879
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ceca.2018.07.003
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