Connexin-43-dependent ATP release mediates macrophage activation during sepsis

Bacterial spillage into a sterile environment following intestinal hollow-organ perforation leads to peritonitis and fulminant sepsis. Outcome of sepsis critically depends on macrophage activation by extracellular ATP-release and associated autocrine signalling via purinergic receptors. ATP-release...

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Vydáno v:eLife
Hlavní autoři: Dosch, Michel, Zindel, Joël, Jebbawi, Fadi, Melin, Nicolas, Sanchez-Taltavull, Daniel, Stroka, Deborah, Candinas, Daniel, Beldi, Guido
Médium: Artigo
Jazyk:Inglês
Vydáno: eLife Sciences Publications, Ltd 2019
Témata:
Immunology and Inflammation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415938/
https://ncbi.nlm.nih.gov/pubmed/30735126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.42670
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