Culture and Real-time Polymerase Chain reaction sensitivity in the diagnosis of invasive meningococcal disease: Does culture miss less severe cases?

BACKGROUND: Invasive meningococcal disease (IMD) is a highly lethal disease. Diagnosis is commonly performed by culture or Realtime-PCR (qPCR). AIMS: Our aim was to evaluate, retrospectively, whether culture positivity correlates with higher bacterial load and fatal outcome. Our secondary aim was to...

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Dettagli Bibliografici
Pubblicato in:PLoS One
Autori principali: Guiducci, Sara, Moriondo, Maria, Nieddu, Francesco, Ricci, Silvia, De Vitis, Elisa, Casini, Arianna, Poggi, Giovanni Maria, Indolfi, Giuseppe, Resti, Massimo, Azzari, Chiara
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2019
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Research Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415896/
https://ncbi.nlm.nih.gov/pubmed/30865671
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0212922
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