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Intestinal bile acid sequestration improves glucose control by stimulating hepatic miR-182-5p in type 2 diabetes

Colesevelam is a bile acid sequestrant approved to treat both hyperlipidemia and type 2 diabetes, but the mechanism for its glucose-lowering effects is not fully understood. The aim of this study was to investigate the role of hepatic microRNAs (miRNAs) as regulators of metabolic disease and to inve...

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Publicat a:Am J Physiol Gastrointest Liver Physiol
Autors principals: Sedgeman, Leslie R., Beysen, Carine, Allen, Ryan M., Ramirez Solano, Marisol A., Turner, Scott M., Vickers, Kasey C.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2018
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415711/
https://ncbi.nlm.nih.gov/pubmed/30160993
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpgi.00238.2018
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