Caffeine Treatment Promotes Differentiation and Maturation of Hypoxic Oligodendrocytes via Counterbalancing Adenosine 1 Adenosine Receptor-Induced Calcium Overload

BACKGROUND: We aimed to explore the involvement of adenosine 1 adenosine receptor (A1AR) in hypoxia-induced poor differentiation of oligodendrocytes (OLs), and the underlying mechanism of caffeine treatment in hypoxic injuries. MATERIAL/METHODS: Real-time polymerase chain reaction (RT-PCR) was used...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Med Sci Monit
Main Authors: Cao, Ting, Ma, Teng, Xu, Yang, Tian, Yanping, Cai, Qiyan, Li, Baichuan, Li, Hongli
Format: Artigo
Jezik:Inglês
Izdano: International Scientific Literature, Inc. 2019
Teme:
Animal Study
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415592/
https://ncbi.nlm.nih.gov/pubmed/30840612
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.12659/MSM.915147
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