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Chitosan in Non-Viral Gene Delivery: Role of Structure, Characterization Methods, and Insights in Cancer and Rare Diseases Therapies

Non-viral gene delivery vectors have lagged far behind viral ones in the current pipeline of clinical trials of gene therapy nanomedicines. Even when non-viral nanovectors pose less safety risks than do viruses, their efficacy is much lower. Since the early studies to deliver pDNA, chitosan has been...

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Detalhes bibliográficos
Publicado no:Polymers (Basel)
Main Authors: Santos-Carballal, Beatriz, Fernández Fernández, Elena, Goycoolea, Francisco M.
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6415274/
https://ncbi.nlm.nih.gov/pubmed/30966479
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/polym10040444
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