Tumor Hypoxia Directed Multimodal Nanotherapy for Overcoming Drug Resistance in Renal Cell Carcinoma and Reprogramming Macrophages

Drug resistance is one of the significant clinical burden in renal cell carcinoma (RCC). The development of drug resistance is attributed to many factors, including impairment of apoptosis, elevation of carbonic anhydrase IX (CA IX, a marker of tumor hypoxia), and infiltration of tumorigenic immune...

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Udgivet i:Biomaterials
Main Authors: Alsaab, Hashem O., Sau, Samaresh, Alzhrani, Rami M., Cheriyan, Vino T., Polin, Lisa A., Vaishampayan, Ulka, Rishi, Arun K., Iyer, Arun K.
Format: Artigo
Sprog:Inglês
Udgivet: 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6414719/
https://ncbi.nlm.nih.gov/pubmed/30179778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2018.08.053
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